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Home / Encyclopedia / Muscle, IGF & Body Composition
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Muscle, IGF & Body Composition.

IGF, myostatin and growth-factor pathway compounds studied for muscle and body composition.

Muscle, IGF & Body Composition

5-Amino-1MQ

5-Amino-1-methylquinolinium (5-Amino-1MQ) is a cell-permeable small-molecule inhibitor of …

Muscle, IGF & Body Composition

ACE-031

ACE-031 (sotatercept precursor) is a fusion protein of ActRIIA (activin receptor type IIA)…

Muscle, IGF & Body Composition

AICAR

AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) is a cell-permeable AMP-mimetic that…

Muscle, IGF & Body Composition

Abaloparatide

Abaloparatide is a synthetic 34-amino-acid analogue of PTHrP (parathyroid hormone-related …

Muscle, IGF & Body Composition

Follistatin-344

Follistatin-344 is a glycoprotein that binds and neutralises myostatin (GDF-8) — the body’…

Muscle, IGF & Body Composition

IGF-1 DES

IGF-1 DES (des(1-3)IGF-1) is a truncated form of IGF-1 lacking the first three N-terminal …

Muscle, IGF & Body Composition

IGF-1 LR3

IGF-1 LR3 (Long R3 IGF-1) is a 83-amino acid analogue of Insulin-like Growth Factor 1 with…

Muscle, IGF & Body Composition

L-Carnitine

L-Carnitine is a naturally occurring amino acid derivative essential for the transport of …

Muscle, IGF & Body Composition

MGF

MGF (Mechano Growth Factor) is a splice variant of IGF-1 produced in skeletal muscle in re…

Muscle, IGF & Body Composition

Melanotan-1

Melanotan-1 (afamelanotide) is a synthetic analogue of alpha-melanocyte-stimulating hormon…

Muscle, IGF & Body Composition

Melanotan-2

Melanotan-2 (MT-2) is a cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormo…

Muscle, IGF & Body Composition

PEG-MGF

PEG-MGF (Pegylated Mechano Growth Factor) is a PEGylated form of MGF, a splice variant of …

Muscle, IGF & Body Composition

PT-141

PT-141 (bremelanotide) is a cyclic heptapeptide derived from Melanotan-2 that selectively …

Muscle, IGF & Body Composition

SLU-PP-332

SLU-PP-332 is a synthetic ERR (Estrogen-Related Receptor) alpha/gamma agonist that activat…

Muscle, IGF & Body Composition

SS-31 (Elamipretide)

SS-31 (Elamipretide, MTP-131) is a mitochondria-targeting tetrapeptide that selectively co…

Muscle, IGF & Body Composition

Setmelanotide

Setmelanotide (Imcivree) is a melanocortin-4 receptor (MC4R) agonist approved for rare genetic obesity syndromes and, since March 2026, for…

Muscle, IGF & Body Composition

Teriparatide

Teriparatide is a recombinant fragment of human parathyroid hormone (PTH 1-34) that, unlike constantly elevated PTH, builds new bone when…

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