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Senolytic & — Senomorphic
Senescent "zombie" cells accumulate with age and release toxic inflammatory signals. Senolytics clear them. This is one of the most exciting areas in longevity science.
SENOLYTICS — KILL ZOMBIE CELLS
Selectively induce apoptosis in senescent cells. Used intermittently — typically one 2-day cycle per month or quarter, not daily.
🔴 Dasatinib + Quercetin (D+Q)
🌼 Fisetin (20mg/kg, 2-day cycles)
🟡 Quercetin (high dose, intermittent)
SENOMORPHICS — SUPPRESS SASP
Do not kill senescent cells but suppress the inflammatory signals they release (SASP). Can be used daily. Lower risk profile.
🔵 Rapamycin (low dose, weekly)
💊 Metformin (daily, physician needed)
🌿 Quercetin (low dose, daily)
Read: Senolytics & senomorphics — clearing zombie cells
Full deep dive including D+Q protocol and peptide synergies
PEPTIDE CONNECTION
After senolytic clearance, your body needs to regenerate tissue. BPC-157 supports tissue repair, GHK-Cu promotes regeneration, and MOTS-C improves the metabolic environment that drives senescence accumulation. Many researchers combine senolytic cycles with peptide protocols for this reason.