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Senolytic & — Senomorphic

Senescent "zombie" cells accumulate with age and release toxic inflammatory signals. Senolytics clear them. This is one of the most exciting areas in longevity science.

SENOLYTICS — KILL ZOMBIE CELLS

Selectively induce apoptosis in senescent cells. Used intermittently — typically one 2-day cycle per month or quarter, not daily.

🔴 Dasatinib + Quercetin (D+Q)

🌼 Fisetin (20mg/kg, 2-day cycles)

🟡 Quercetin (high dose, intermittent)

SENOMORPHICS — SUPPRESS SASP

Do not kill senescent cells but suppress the inflammatory signals they release (SASP). Can be used daily. Lower risk profile.

🔵 Rapamycin (low dose, weekly)

💊 Metformin (daily, physician needed)

🌿 Quercetin (low dose, daily)

Read: Senolytics & senomorphics — clearing zombie cells

Full deep dive including D+Q protocol and peptide synergies

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PEPTIDE CONNECTION

After senolytic clearance, your body needs to regenerate tissue. BPC-157 supports tissue repair, GHK-Cu promotes regeneration, and MOTS-C improves the metabolic environment that drives senescence accumulation. Many researchers combine senolytic cycles with peptide protocols for this reason.