PeptideCompareSLU-PP-332 — EU research guide.
SLU-PP-332 is a synthetic ERR (Estrogen-Related Receptor) alpha/gamma agonist that activates the same transcriptional programme as endurance exercise. It is studied as an exercise mimetic in metabolic and muscle biology research.
What is SLU-PP-332?
SLU-PP-332 activates ERRα and ERRγ, nuclear receptors that coordinate the transcriptional response to endurance exercise — upregulating mitochondrial biogenesis, fatty acid oxidation, and slow-twitch muscle fibre programming via PGC-1α co-activation. It was developed by Thomas Burris and colleagues at University of Florida.
What does the research show?
In mouse studies, SLU-PP-332-treated animals showed improved running endurance (~70% increase in time to exhaustion), increased mitochondrial density in muscle, and reduced fat accumulation. The effect profile is complementary to AICAR (AMPK activation) but works through a distinct nuclear receptor pathway. No human data exists as of mid-2026.
EU legal status
Research compound only. Not approved anywhere. Available from EU vendors for laboratory exercise biology research. WADA status not currently assessed — may be subject to review as research advances.
Molecular information
Pharmacokinetics
Potency retained over time
Each line is one storage condition: it starts at 100% and falls as potency is lost. Above the dashed 80% line the material is considered reliable — hover for exact values.
⚠ Computed from molecular properties (sequence length, cyclisation, residues prone to oxidation or deamidation, light sensitivity), per compound. Indicative only — not lab-measured per batch.
SLU-PP-332 across EU suppliers
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