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Home / Encyclopedia / Recovery & Healing / Thymosin Alpha-1
MONOGRAPH No. 097
EVIDENCE BASEStrong
SEQUENCE
28 amino acids
MW
3108 g/mol
CAS
62304-98-7
APPROVED AS
Zadaxin (30+ countries)
EU STATUS
Research only
MIN PURITY
≥98% HPLC
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🧬 Recovery & Healing

Thymosin Alpha-1 — the immune modulator.

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide naturally produced by the thymus gland. It is an approved drug in over 30 countries (as Zadaxin) for immune-related conditions, making it one of the better-validated peptides in this category.

Last reviewed:

What is Thymosin Alpha-1?

Thymosin Alpha-1 is a naturally occurring thymic peptide central to T-cell maturation and immune regulation. It enhances the function of immune cells (T-cells, dendritic cells, NK cells) and modulates inflammatory responses. It is approved as Zadaxin in many countries for hepatitis B/C, as a vaccine adjuvant, and as an immune support agent — though not approved in the EU or US.

What does the research show?

EVIDENCE SUMMARY
STRONG
Immune modulation — Extensive clinical data supporting its approval in 30+ countries. Enhances T-cell and NK-cell function.
MODERATE
Antiviral adjunct — Clinical use as adjunct in hepatitis B/C and as a vaccine adjuvant in approved markets.
MODERATE
Sepsis & critical illness — Studied during COVID-19 and in sepsis with mixed-to-encouraging results.
Approved as a pharmaceutical (Zadaxin) in many countries but not in the EU. Research-grade product sold in Europe is for laboratory research only and is not the approved drug. This is a research compound, not a medication.

What to look for when buying in Europe

Among the better-validated peptides clinically. Research-grade Tα1 should be ≥98% HPLC with mass-spec confirmation. PeptideCompare tracks several EU vendors.

✓ PeptideCompare tracks Thymosin Alpha-1 from 7 COA-verified EU vendors, starting from €30.19. Prices move month to month and differ by vendor; compare before ordering.

Molecular information

Molecular formula
C129H215N33O55
Molecular weight
3108 g/mol
CAS number
62304-98-7

Pharmacokinetics

No established human pharmacokinetic data. Published human PK parameters for this compound are not available; reported data are limited to animal models or absent. No curve is shown, to avoid implying data that does not exist.

Compare Thymosin Alpha-1 across EU suppliers

7 EU vendors · COA-verified · from €30.19 · Updated monthly

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