PeptideCompareGHRP-2 — EU research guide.
GHRP-2 (Growth Hormone Releasing Peptide-2, Pralmorelin) is a synthetic hexapeptide ghrelin mimetic that stimulates GH release via the ghrelin receptor (GHS-R1a). It is more potent and has less appetite-stimulating effect than GHRP-6.
What is GHRP-2?
GHRP-2 is a synthetic hexapeptide that binds the ghrelin receptor (GHS-R1a) with high affinity, triggering GH release from the anterior pituitary. Unlike Ipamorelin, GHRP-2 also activates the central cortisol and prolactin axes to a moderate degree. It has a stronger GH pulse amplitude than GHRP-6 with less appetite stimulation. It was approved as Pralmorelin for GH stimulation testing in Japan.
What does the research show?
Clinical studies for GH stimulation diagnostics showed reliable and reproducible GH release. Research in cachectic states, post-surgical recovery and GH deficiency models demonstrates anabolic and protective effects. GHRP-2 has been the subject of multiple human pharmacokinetic studies establishing its GH secretion profile.
EU legal status
Not approved as a therapeutic in the EU (approved in Japan for diagnostic use only). WADA-prohibited in sport (S2). Available for laboratory research only.
Molecular information
Pharmacokinetics
Potency retained over time
Each line is one storage condition: it starts at 100% and falls as potency is lost. Above the dashed 80% line the material is considered reliable — hover for exact values.
⚠ Estimates modelled per compound from its molecular properties (sequence length, cyclisation, oxidation- and deamidation-prone residues, light sensitivity). Indicative only — not lab-measured per batch.
GHRP-2 across EU suppliers
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Frequently asked questions
What is GHRP-2? ▾
GHRP-2 is a synthetic hexapeptide that binds the ghrelin receptor (GHS-R1a) with high affinity to trigger GH release from the anterior pituitary. It was approved as Pralmorelin for GH stimulation testing in Japan.
How does GHRP-2 compare to Ipamorelin and GHRP-6? ▾
It produces a stronger GH pulse amplitude than GHRP-6 with less appetite stimulation, but unlike ipamorelin it also moderately activates the cortisol and prolactin axes.
What does the research show? ▾
Clinical studies for GH stimulation diagnostics showed reliable, reproducible GH release, and research in cachexia, post-surgical recovery and GH-deficiency models shows anabolic and protective effects.
Does GHRP-2 raise cortisol and prolactin? ▾
Yes, to a moderate degree, which distinguishes it from the more selective ipamorelin.
Is GHRP-2 legal in the EU? ▾
It is not approved as a therapeutic in the EU, though it is approved in Japan for GH stimulation testing, and is sold as a research compound for laboratory use only.
Is GHRP-2 banned in sport? ▾
Yes. It appears on the WADA prohibited list (S2).