PeptideComparePeptide storage & stability
Improper storage is the most common cause of peptide degradation outside the lab. Lyophilized vials and reconstituted solutions need fundamentally different handling.
| FORM | TEMP | SHELF LIFE | NOTES |
|---|---|---|---|
| Lyophilized (sealed) | −20°C ideal | 1–3+ years | Light/moisture bigger risks than heat short-term |
| Reconstituted (fridge) | 2–8°C | 4–6 weeks | BAC water extends vs sterile water |
| Reconstituted (frozen) | −20°C | 3–6 months | Freeze-thaw cycles degrade faster |
| Room temp (open) | 20–25°C | Hours–days | Reconstituted peptide at RT degrades fast |
Freeze-thaw cycles: the hidden risk
Every freeze-thaw cycle stresses peptide bonds through ice crystal formation. Most peptides tolerate 3–5 cycles before measurable degradation. For large reconstituted vials, consider aliquoting into smaller volumes before freezing — thaw only what you need.
Light and UV degradation
Several peptides (melanocortins like MT-2 and PT-141, and some GHRPs) are light-sensitive. Store vials in their original box or a dark drawer. Amber vials offer partial protection but are not sufficient for highly light-sensitive compounds during extended storage.
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