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MONOGRAPH No. 011
SEQUENCE
Glu-Asp-Arg (3 AA)
MW
418.4 g/mol
CAS
175175-23-2
EU STATUS
Research only
WADA
Not listed
MIN PURITY
≥98% HPLC
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⏳ Anti-Aging & Longevity

Pinealon — EU research guide.

Pinealon (Glu-Asp-Arg) is a synthetic tripeptide bioregulator targeting pineal gland and brain tissue. It is studied for circadian rhythm support, neuroprotection and sleep quality in Russian gerontological research.

Last reviewed:

What is Pinealon?

Pinealon is a short-sequence bioregulator from the Khavinson peptide series. It is proposed to target pineal gland and neuronal tissue, modulating expression of genes involved in melatonin synthesis and circadian regulation. The tripeptide structure allows cell penetration and proposed interaction with nucleosomal DNA.

What does the research show?

Russian preclinical studies report neuroprotective effects in oxidative stress models, improved spatial memory in aged rats, and melatonin pathway modulation. Some human observational studies in elderly cohorts suggest improved sleep quality metrics. Evidence is limited to Russian-language literature and small studies without placebo-controlled replication in Western journals.

EU legal status

Not approved as a medicine in the EU. Available from specialist EU research vendors as a laboratory compound for neuroscience research.

Evidence predominantly from non-replicated Russian institutional studies. Not for human use. This is a research compound, not a medication.
✓ PeptideCompare monitors Pinealon from EU vendors. Request HPLC purity ≥98% and sequence confirmation.

Molecular information

Molecular formula
C15H26N6O8
Molecular weight
418.4 g/mol
CAS number
175175-23-2

Pharmacokinetics

No established human pharmacokinetic data. Published human PK parameters for this compound are not available; reported data are limited to animal models or absent. No curve is shown, to avoid implying data that does not exist.

Pinealon across EU suppliers

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