⚠ Research and educational use only — not for human consumption. Nothing for sale, no dosing advice. PeptideCompare is non-profit and independent.
Database Suppliers Quality & badges Supplier reviews Encyclopedia Articles Calculator
LONGEVITY TOPICS
NAD+ Precursors Sirtuin Activators Senolytics Autophagy Mitochondrial Hormesis
About FAQ Contact Policy
MONOGRAPH No. 001
SEQUENCE
Ala-His-Lys + Cu²⁺
MW
~424 Da
CAS
130120-57-9
EU STATUS
Research / Cosmetic
WADA
Not listed
MIN PURITY
≥95% HPLC
View prices →
⏳ Anti-Aging & Longevity

AHK-Cu — EU research guide.

AHK-Cu (Alanyl-Histidyl-Lysine copper complex) is a copper-binding tripeptide studied for hair growth stimulation and dermal repair, structurally related to GHK-Cu but with distinct receptor interactions.

Last reviewed:

What is AHK-Cu?

AHK-Cu is a tripeptide that chelates copper(II) to form a stable complex. Like GHK-Cu it activates copper-dependent enzymes involved in collagen synthesis and tissue remodelling, but its distinct amino acid sequence gives it preferential activity in hair follicle research. It is used in cosmetic research to study anagen phase prolongation.

What does the research show?

In vitro and animal studies suggest AHK-Cu stimulates hair follicle cell proliferation and extends the anagen (growth) phase. Some comparative studies indicate stronger hair-specific activity than GHK-Cu. Dermal wound healing and collagen upregulation are also documented in preclinical models. No clinical trials published as of mid-2026.

EU legal status

AHK-Cu is used in both cosmetic formulations (where it is a legal cosmetic ingredient under EU Cosmetics Regulation 1223/2009) and as a research compound. Injectable research-grade AHK-Cu is sold for laboratory use only.

No human clinical trial data for injectable AHK-Cu. Cosmetic ingredient ≠ research compound. Not for human injection. This is a research compound, not a medication.
✓ PeptideCompare tracks AHK-Cu from EU vendors. Look for lyophilised powder with HPLC purity ≥95% and copper content verification.
EVIDENCE SUMMARY
MODERATE
Hair follicle signalling — Copper-tripeptide studied for follicle stimulation and vascularisation in cosmetic research.
LIMITED
Angiogenesis & skin — Copper-dependent effects on angiogenesis and skin, analogous to GHK-Cu; limited data.

Molecular information

Molecular weight
~424 Da
CAS number
130120-57-9

Pharmacokinetics

Half-life (t½)
≈ 1.5 h
Source: Estimate, analogous to GHK-Cu (~1–2 h)

Potency retained over time

Each line is one storage condition: it starts at 100% and falls as potency is lost. Above the dashed 80% line the material is considered reliable — hover for exact values.

Freezer −20 °C
36+ mo
Stable · >95% potency
Fridge 4 °C
3-4 mo
In use · after recon
Room 20 °C
2-3 wks
Limited · moderate loss
Warm 37 °C+
2-3 days
Critical · rapid degradation

⚠ A structural estimate, derived from each compound's sequence length, cyclisation and oxidation-, deamidation- and light-sensitive residues. Indicative only — not lab-measured per batch.

AHK-Cu across EU suppliers

COA-verified EU vendors · Updated monthly

Related guides

PeptideCompare AssistantOnline · replies instantly
Hi! I help you quickly find the right page — about legality, COAs, badges or suppliers. No price advice, no dosing.
Try a question
Find a supplier Questions about a peptide? Read our articles Compare prices
Navigation assistant · no medical advice