PeptideCompareNAD+ — the cellular energy coenzyme.
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme present in every living cell, central to energy metabolism, DNA repair, and sirtuin activation. Cellular levels decline with age, driving major longevity research interest.
What is NAD+?
NAD+ is a coenzyme found in all cells, essential for converting nutrients into cellular energy (ATP) and for activating sirtuins — enzymes involved in DNA repair and longevity signalling. NAD+ levels fall with age. Research approaches include direct NAD+ administration and supplementation with precursors like NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside), which the body converts to NAD+.
What does the research show?
What to look for when buying in Europe
Decide between direct NAD+ and precursors (NMN/NR) — they differ in cost, bioavailability and route. PeptideCompare tracks NAD+ and related compounds. Require purity documentation appropriate to the product type.
Molecular information
Pharmacokinetics
Potency retained over time
Each line is one storage condition: it starts at 100% and falls as potency is lost. Above the dashed 80% line the material is considered reliable — hover for exact values.
⚠ Computed from molecular properties (sequence length, cyclisation, residues prone to oxidation or deamidation, light sensitivity), per compound. Indicative only — not lab-measured per batch.
Compare NAD+ across EU suppliers
10 EU vendors · COA-verified · from €59.95 · Updated monthly
Frequently asked questions
What is NAD+? ▾
NAD+ is a coenzyme present in all cells, essential for converting nutrients into cellular energy (ATP) and for activating sirtuins, enzymes involved in DNA repair and longevity signalling. NAD+ levels decline with age.
What is the difference between NAD+ and precursors like NMN or NR? ▾
Precursors such as NMN and NR are converted by the body into NAD+ and are sold as supplements in many countries. Direct injectable NAD+ has less established safety data, and its bioavailability remains debated.
What does the research show? ▾
NAD+ is foundational for ATP production and hundreds of metabolic reactions, and human data consistently shows tissue NAD+ declining with age. The sirtuin and DNA-repair mechanisms are well supported, though clinical longevity outcomes are still emerging.
Is injectable NAD+ safe? ▾
Injectable NAD+ for research has less established safety data than oral precursors, and injection-site discomfort is commonly reported. Without completed trials, the human safety profile is not established.
Is NAD+ legal in the EU? ▾
NAD+ precursors (NMN, NR) are sold as supplements in many countries. Injectable NAD+ is handled as a research compound for laboratory use only.
Oral precursor or injection? ▾
The optimal route is debated. Oral NMN or NR versus injection each carry trade-offs in bioavailability, and current evidence does not settle the question.