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Home / Encyclopedia / GLP-1 & Weight / Liraglutide
MONOGRAPH No. 033
SEQUENCE
26 amino acids
MW
3751.2 g/mol
CAS
204656-20-2
EU STATUS
Rx-only / Research
WADA
Not prohibited
MIN PURITY
≥98% HPLC
⚖ GLP-1 & Weight

Liraglutide — EU research guide.

Liraglutide is a GLP-1 receptor agonist developed by Novo Nordisk and approved as Victoza (diabetes) and Saxenda (obesity). As a research peptide it is studied for metabolic and neuroprotective mechanisms.

Last reviewed:

What is Liraglutide?

Liraglutide is a fatty-acid acylated GLP-1 analogue with a half-life of ~13 hours, allowing once-daily dosing in clinical use. It binds and activates the GLP-1 receptor, stimulating insulin secretion and suppressing glucagon in a glucose-dependent manner. As a research peptide it is used to study GLP-1 receptor pharmacology, beta-cell biology and neuroinflammation models.

What does the research show?

Clinical trials (SCALE, LEADER) established liraglutide efficacy for weight loss (~5–8% body weight) and cardiovascular risk reduction in type-2 diabetes. Preclinical research additionally suggests neuroprotective properties in Alzheimer’s and Parkinson’s disease models via GLP-1 receptor activation in the brain. Research-grade liraglutide is used to replicate and extend these mechanistic studies.

EU legal status

Liraglutide is an EMA-approved prescription medicine (Victoza, Saxenda). Research-grade liraglutide is sold by EU vendors for in-vitro and preclinical research only. Importation or use outside a licensed medical context carries regulatory risk in all EU member states.

⚠ EMA-approved prescription drug. Research-grade liraglutide is not the approved pharmaceutical and is not for human use. This is a research compound, not a medication.
✓ PeptideCompare tracks liraglutide purity and pricing across COA-verified EU vendors.

Molecular information

Molecular formula
C172H265N43O51
Molecular weight
3751.2 g/mol
CAS number
204656-20-2

Pharmacokinetics

Half-life (t½)
≈ 13 h
Tmax
≈ 10 h
Source: FDA Victoza label; StatPearls (NBK608007)

Liraglutide across EU suppliers

COA-verified EU vendors · Updated monthly

Frequently asked questions

What is Liraglutide? ▾

Liraglutide is a fatty-acid acylated GLP-1 analog with a half-life of about 13 hours, allowing once-daily dosing. It activates the GLP-1 receptor, stimulating insulin secretion and suppressing glucagon in a glucose-dependent manner.

What does the research show? ▾

Clinical trials (SCALE, LEADER) established efficacy for weight loss of roughly 5 to 8% of body weight and cardiovascular risk reduction in type 2 diabetes, and preclinical research suggests neuroprotective properties in Alzheimer's and Parkinson's models.

How does liraglutide compare to semaglutide? ▾

Liraglutide is dosed once daily with roughly 5 to 8% weight loss, whereas newer analogs like semaglutide and tirzepatide are once-weekly with larger weight-loss effects.

Is liraglutide legal in the EU? ▾

The pharmaceutical form is prescription-only. Research-grade liraglutide is used to study GLP-1 receptor pharmacology in the laboratory.

Is liraglutide banned in sport? ▾

No. It is not prohibited by WADA.

Does liraglutide have brain effects? ▾

Preclinical research suggests neuroprotective properties in Alzheimer's and Parkinson's models via GLP-1 receptor activation in the brain, though this is not clinically established.

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