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Home / Encyclopedia / GLP-1 & Weight / Liraglutide
MONOGRAPH No. 033
SEQUENCE
26 amino acids
MW
3751.2 g/mol
CAS
204656-20-2
EU STATUS
Rx-only / Research
WADA
Not prohibited
MIN PURITY
≥98% HPLC
⚖ GLP-1 & Weight

Liraglutide — EU research guide.

Liraglutide is a GLP-1 receptor agonist developed by Novo Nordisk and approved as Victoza (diabetes) and Saxenda (obesity). As a research peptide it is studied for metabolic and neuroprotective mechanisms.

Last reviewed:

What is Liraglutide?

Liraglutide is a fatty-acid acylated GLP-1 analogue with a half-life of ~13 hours, allowing once-daily dosing in clinical use. It binds and activates the GLP-1 receptor, stimulating insulin secretion and suppressing glucagon in a glucose-dependent manner. As a research peptide it is used to study GLP-1 receptor pharmacology, beta-cell biology and neuroinflammation models.

What does the research show?

Clinical trials (SCALE, LEADER) established liraglutide efficacy for weight loss (~5–8% body weight) and cardiovascular risk reduction in type-2 diabetes. Preclinical research additionally suggests neuroprotective properties in Alzheimer’s and Parkinson’s disease models via GLP-1 receptor activation in the brain. Research-grade liraglutide is used to replicate and extend these mechanistic studies.

EU legal status

Liraglutide is an EMA-approved prescription medicine (Victoza, Saxenda). Research-grade liraglutide is sold by EU vendors for in-vitro and preclinical research only. Importation or use outside a licensed medical context carries regulatory risk in all EU member states.

EMA-approved prescription drug. Research-grade liraglutide is not the approved pharmaceutical and is not for human use. This is a research compound, not a medication.
✓ PeptideCompare tracks liraglutide purity and pricing across COA-verified EU vendors.

Molecular information

Molecular formula
C172H265N43O51
Molecular weight
3751.2 g/mol
CAS number
204656-20-2

Pharmacokinetics

Route
Subcutaneous
Half-life (t½)
≈13 h
Tmax
8–12 h
Bioavailability
≈55% (SC)
Source: FDA Victoza label; StatPearls (NBK608007)
Research context only — not dosing guidance.

Liraglutide across EU suppliers

COA-verified EU vendors · Updated monthly

Frequently asked questions

What is Liraglutide?

Liraglutide is a fatty-acid acylated GLP-1 analog with a half-life of about 13 hours, allowing once-daily dosing. It activates the GLP-1 receptor, stimulating insulin secretion and suppressing glucagon in a glucose-dependent manner.

What does the research show?

Clinical trials (SCALE, LEADER) established efficacy for weight loss of roughly 5 to 8% of body weight and cardiovascular risk reduction in type 2 diabetes, and preclinical research suggests neuroprotective properties in Alzheimer's and Parkinson's models.

How does liraglutide compare to semaglutide?

Liraglutide is dosed once daily with roughly 5 to 8% weight loss, whereas newer analogs like semaglutide and tirzepatide are once-weekly with larger weight-loss effects.

Is liraglutide legal in the EU?

The pharmaceutical form is prescription-only. Research-grade liraglutide is used to study GLP-1 receptor pharmacology in the laboratory.

Is liraglutide banned in sport?

No. It is not prohibited by WADA.

Does liraglutide have brain effects?

Preclinical research suggests neuroprotective properties in Alzheimer's and Parkinson's models via GLP-1 receptor activation in the brain, though this is not clinically established.

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