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MONOGRAPH No. 133
SEQUENCE
N/A (nucleotide, not a peptide)
MW
507.18 g/mol
CAS
56-65-5
EU STATUS
Research only
WADA
Not listed
MIN PURITY
≥98% HPLC
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🧠 Neuro & Cognitive

ATP — EU research guide.

ATP (adenosine triphosphate) is the cell’s primary energy-carrying nucleotide, used in research on cellular metabolism and energy homeostasis.

Last reviewed:

What is ATP?

ATP is a nucleotide built from adenine, ribose and three phosphate groups. It is the universal energy carrier in living cells: hydrolysis of the terminal phosphate bond releases the energy that drives nearly every cellular process, from muscle contraction to active membrane transport. Unlike most substances in this database, ATP is not a peptide but a nucleotide, and it occurs naturally in every cell.

What does the research show?

ATP’s role in cellular metabolism is extensively documented. Less clear is what oral or parenteral administration of free ATP actually achieves: extracellular ATP is very rapidly broken down by ecto-nucleotidases, and how much orally administered ATP reaches the bloodstream intact is debated. A small number of studies on oral ATP in athletes report modest effects on muscle strength and recovery; the evidence base is limited and not consistently replicated.

EU legal status

ATP is a naturally occurring substance and not a regulated medicine; available as a research chemical from specialised suppliers.

Oral bioavailability of free ATP is debated — it is rapidly broken down extracellularly. Limited and inconsistently replicated human research. Not for human use. This is a research chemical, not a medicine.
✓ PeptideCompare monitors ATP across EU research suppliers. ATP is not a peptide — don’t mistake sequence-like naming in supplier catalogues for an amino acid chain.

Molecular information

Molecular formula
C10H16N5O13P3
Molecular weight
507.18 g/mol
CAS number
56-65-5

Pharmacokinetics

No established pharmacokinetics for exogenous (oral) ATP administration in humans — the oral bioavailability of intact ATP is disputed in the literature. No curve is shown, to avoid suggesting data that doesn’t exist.

Potency retained over time

Each line is one storage condition: it starts at 100% and declines as potency is lost. Above the dotted 80% line the material is considered reliable — hover the chart for exact values.

Freezer −20 °C
36+ mo
Stable · >95% potency
Fridge 4 °C
5-7 mo
In use · post-recon
Room 20 °C
3-4 wks
Limited · moderate loss
Warm 37 °C+
2-3 days
Poor · rapid loss

⚠ Estimates modelled per component from molecular properties (chain length, cyclisation, oxidation- and deamidation-sensitive residues, light sensitivity). Indicative only — not lab-measured per batch.

ATP across EU suppliers

COA-verified EU vendors · Updated monthly

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