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Home / Encyclopedia / Growth Hormone Axis / Sermorelin vs Tesamorelin
⚖️ Growth Hormone Axis

Sermorelin vs Tesamorelin

How do Sermorelin and Tesamorelin compare for Growth Hormone Axis research? Side-by-side evidence, molecular profile, EU legal status and COA-verified supplier prices — never dosing advice.

At a glance

Sermorelin

⚡ Growth Hormone Axis
EVIDENCE BASEStrong
CLASS
GHRH(1-29)
MW
3358 g/mol
CAS
86168-78-7
EU STATUS
Research only
WADA
Prohibited S2
MIN PURITY
≥98% HPLC
Molecular weight
3358 g/mol
CAS number
86168-78-7
Route
Subcutaneous
Half-life (t½)
≈11–12 min
PRICE FROM
€31.45 · 6 EU vendors
View prices →

Tesamorelin

⚡ Growth Hormone Axis
EVIDENCE BASEStrong
CLASS
GHRH analog
MW
5135.9 g/mol
CAS
218949-48-5
APPROVED AS
Egrifta (HIV)
EU STATUS
Research only
WADA
Prohibited S2
Molecular weight
5135.9 g/mol
CAS number
218949-48-5
Route
Subcutaneous
Half-life (t½)
≈32 min
PRICE FROM
€33.97 · 11 EU vendors
View prices →

Which fits which research target?

Both Sermorelin and Tesamorelin sit within Growth Hormone Axis research but are studied for different primary signals. Neither is an approved medicine — compare the evidence, not marketing claims.

PRIMARY RESEARCH SIGNAL
Sermorelin
GH/IGF-1 elevation
Tesamorelin
Visceral fat reduction
Neither Sermorelin nor Tesamorelin is an approved medicine. All comparisons here are research observations, not usage, dosing or efficacy recommendations.

What the research shows

Sermorelin

EVIDENCE SUMMARY
STRONG
GH/IGF-1 elevation — Well-established stimulation of pituitary GH release and downstream IGF-1. Historically used as a diagnostic agent for GH deficiency.
MODERATE
Body composition (with stacking) — Often combined with a GHRP like Ipamorelin. Some data on improved body composition and sleep quality.
LIMITED
Anti-aging claims — Short half-life limits sustained effect. Longevity claims are largely extrapolated from GH/IGF-1 elevation.

Tesamorelin

EVIDENCE SUMMARY
STRONG
Visceral fat reduction — FDA-approved for this indication. Clinical trials show significant reduction in visceral adipose tissue in HIV lipodystrophy.
STRONG
GH/IGF-1 elevation — Reliably raises GH and IGF-1 through pituitary stimulation.
MODERATE
Cognitive / other — Some research interest in cognition in older adults; smaller evidence base.

Compare prices across EU suppliers

Compare Sermorelin across EU suppliers

6 EU vendors · COA · from €31.45

View prices →

Compare Tesamorelin across EU suppliers

11 EU vendors · COA · from €33.97

View prices →

Frequently asked questions

Is Sermorelin or Tesamorelin better?

Neither is an approved medicine, and “better” depends on the research target. Sermorelin is most associated with GH/IGF-1 elevation, while Tesamorelin is studied for Visceral fat reduction. Compare the evidence tiers and COA-verified EU pricing above rather than assuming one is superior. This is not a usage recommendation.

Why compare Sermorelin and Tesamorelin?

Both are studied within Growth Hormone Axis research through different mechanisms, so researchers often weigh them against each other. This page sets their evidence, molecular profile, EU legal status and supplier pricing side by side.

Which is cheaper in the EU, Sermorelin or Tesamorelin?

Prices vary by supplier, vial size and COA status. Sermorelin is listed from €31.45 across 6 COA-verified EU vendors; Tesamorelin from €33.97 across 11. Open the price pages above to compare current listings — nobody pays us for placement.

Read the full guides

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