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⚖️ Muscle, IGF & Body Composition

PT-141 vs Melanotan-2

How do PT-141 and Melanotan-2 compare for Muscle, IGF & Body Composition research? Side-by-side evidence, molecular profile, EU legal status and COA-verified supplier prices — never dosing advice.

At a glance

PT-141

💪 Muscle, IGF & Body Composition
EVIDENCE BASE
SEQUENCE
Cyclic heptapeptide (MT-2 derived)
MW
1025.2 g/mol
CAS
189691-06-3
EU STATUS
Not EMA-approved · Research
WADA
Not listed
MIN PURITY
≥98% HPLC
Molecular weight
1025.2 g/mol
CAS number
189691-06-3
Route
Subcutaneous
Half-life (t½)
≈2.7 h
Tmax
≈1.0 h
Bioavailability
≈100% (SC)
PRICE FROM
€22.63 · 12 EU vendors
View prices →

Melanotan-2

💪 Muscle, IGF & Body Composition
EVIDENCE BASE
CLASS
Melanocortin agonist
MW
1024.2 g/mol
CAS
121062-08-6
EU STATUS
Varies by country
UK STATUS
Prescription only
WADA
Prohibited S0
Molecular weight
1024.2 g/mol
CAS number
121062-08-6
Route
Subcutaneous
Half-life (t½)
≈30–60 min
PRICE FROM
€29.9 · 9 EU vendors
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Which fits which research target?

Both PT-141 and Melanotan-2 sit within Muscle, IGF & Body Composition research but are studied for different primary signals. Neither is an approved medicine — compare the evidence, not marketing claims.

Neither PT-141 nor Melanotan-2 is an approved medicine. All comparisons here are research observations, not usage, dosing or efficacy recommendations.

What the research shows

PT-141

FDA approved bremelanotide (Vyleesi) in 2019 for hypoactive sexual desire disorder (HSDD) in premenopausal women. Approval was based on trials showing improved satisfying sexual events and desire scores. Research in male sexual dysfunction shows pro-erectile effects via central pathways. Side effects include transient blood pressure increase and nausea.

Melanotan-2

EVIDENCE SUMMARY
STRONG
Melanogenesis & tanning — Potent MC1R agonist producing skin darkening at low cumulative doses in human studies.
MODERATE
Sexual function — MC4R activation with erectogenic effects — the pathway from which bremelanotide (PT-141) was developed.
LIMITED
Appetite & metabolic — Melanocortin-mediated appetite suppression observed; early-stage.

Compare prices across EU suppliers

Compare PT-141 across EU suppliers

12 EU vendors · COA · from €22.63

View prices →

Compare Melanotan-2 across EU suppliers

9 EU vendors · COA · from €29.9

View prices →

Frequently asked questions

Is PT-141 or Melanotan-2 better?

Neither is an approved medicine, and “better” depends on the research target. PT-141 is most associated with Muscle, IGF & Body Composition, while Melanotan-2 is studied for Melanogenesis & tanning. Compare the evidence tiers and COA-verified EU pricing above rather than assuming one is superior. This is not a usage recommendation.

Why compare PT-141 and Melanotan-2?

Both are studied within Muscle, IGF & Body Composition research through different mechanisms, so researchers often weigh them against each other. This page sets their evidence, molecular profile, EU legal status and supplier pricing side by side.

Which is cheaper in the EU, PT-141 or Melanotan-2?

Prices vary by supplier, vial size and COA status. PT-141 is listed from €22.63 across 12 COA-verified EU vendors; Melanotan-2 from €29.9 across 9. Open the price pages above to compare current listings — nobody pays us for placement.

Read the full guides

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