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⚖️ Anti-Aging & Longevity

MOTS-c vs AOD-9604

How do MOTS-c and AOD-9604 compare for Anti-Aging & Longevity research? Side-by-side evidence, molecular profile, EU legal status and COA-verified supplier prices — never dosing advice.

At a glance

MOTS-c

⏳ Anti-Aging & Longevity

EVIDENCE BASEPreclinical

CLASS

Mitochondrial peptide

2174.5 g/mol

ORIGIN

Mitochondrial 12S rRNA

MECHANISM

AMPK activation

EU STATUS

Research only

PRICE FROM

€29.95 · 25 EU vendors

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AOD-9604

⚖ GLP-1 & Weight

EVIDENCE BASEModerate

CLASS

HGH(176-191) frag

1815.10 g/mol

CAS

221231-10-3

EU STATUS

Research only

WADA

Prohibited S2

MIN PURITY

≥98% HPLC

PRICE FROM

€23.31 · 14 EU vendors

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Which fits which research target?

Both MOTS-c and AOD-9604 sit within Anti-Aging & Longevity research but are studied for different primary signals. Neither is an EU-approved medicine — compare the evidence, not marketing claims.

PRIMARY RESEARCH SIGNAL

MOTS-c

AMPK activation & insulin sensitivity

AOD-9604

Lipolysis (animal)

⚠ Neither MOTS-c nor AOD-9604 is an EU-approved medicine. All comparisons here are research observations, not usage, dosing or efficacy recommendations.

What the research shows

MOTS-c

EVIDENCE SUMMARY

STRONG

AMPK activation & insulin sensitivity — Consistent animal data. Improved insulin sensitivity and glucose metabolism in rodent models including type 2 diabetes models.

MODERATE

Age-related decline (human correlation) — Human studies show declining serum MOTS-C with age, correlation with metabolic health markers. Not causal.

LIMITED

Exercise mimetic effects — Animal data suggesting MOTS-C mimics some beneficial effects of exercise training. Human trial data pending.

AOD-9604

EVIDENCE SUMMARY

MODERATE

Lipolysis (animal) — Animal studies show stimulation of fat breakdown and inhibition of fat accumulation without HGH-like growth effects.

LIMITED

Human weight loss — Human obesity trials by the original developer did not show statistically significant weight loss vs placebo at tested doses.

LIMITED

Cartilage / joint repair — Some preliminary interest in osteoarthritis research.

Compare prices across EU suppliers

Compare MOTS-c across EU suppliers

25 EU vendors · COA · from €29.95

View prices →

Compare AOD-9604 across EU suppliers

14 EU vendors · COA · from €23.31

View prices →

Frequently asked questions

Is MOTS-c or AOD-9604 better? ▾

Neither is an EU-approved medicine, and “better” depends on the research target. MOTS-c is most associated with AMPK activation & insulin sensitivity, while AOD-9604 is studied for Lipolysis (animal). Compare the evidence tiers and COA-verified EU pricing above rather than assuming one is superior. This is not a usage recommendation.

Why compare MOTS-c and AOD-9604? ▾

Both are studied within Anti-Aging & Longevity research through different mechanisms, so researchers often weigh them against each other. This page sets their evidence, molecular profile, EU legal status and supplier pricing side by side.

Which is cheaper in the EU, MOTS-c or AOD-9604? ▾

Prices vary by supplier, vial size and COA status. MOTS-c is listed from €29.95 across 25 COA-verified EU vendors; AOD-9604 from €23.31 across 14. Open the price pages above to compare current listings — nobody pays us for placement.

MOTS-c vs AOD-9604

At a glance

MOTS-c

AOD-9604

Which fits which research target?

What the research shows

MOTS-c

AOD-9604

Compare prices across EU suppliers

Compare MOTS-c across EU suppliers

Compare AOD-9604 across EU suppliers

Frequently asked questions

Read the full guides

MOTS-c

AOD-9604