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Home / Encyclopedia / Anti-Aging & Longevity / MOTS-c vs AOD-9604
⚖️ Anti-Aging & Longevity

MOTS-c vs AOD-9604

How do MOTS-c and AOD-9604 compare for Anti-Aging & Longevity research? Side-by-side evidence, molecular profile, EU legal status and COA-verified supplier prices — never dosing advice.

At a glance

MOTS-c

⏳ Anti-Aging & Longevity
EVIDENCE BASEStrong
CLASS
Mitochondrial peptide
MW
2174.5 g/mol
ORIGIN
Mitochondrial 12S rRNA
MECHANISM
AMPK activation
EU STATUS
Research only
Molecular weight
2174.5 g/mol
PRICE FROM
€29.95 · 19 EU vendors
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AOD-9604

⚖ GLP-1 & Weight
EVIDENCE BASEModerate
CLASS
HGH(176-191) frag
MW
1817 g/mol
CAS
221231-10-3
EU STATUS
Research only
WADA
Prohibited S2
MIN PURITY
≥98% HPLC
Molecular weight
1817 g/mol
CAS number
221231-10-3
PRICE FROM
€21.37 · 12 EU vendors
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Which fits which research target?

Both MOTS-c and AOD-9604 sit within Anti-Aging & Longevity research but are studied for different primary signals. Neither is an approved medicine — compare the evidence, not marketing claims.

PRIMARY RESEARCH SIGNAL
MOTS-c
AMPK activation & insulin sensitivity
AOD-9604
Lipolysis (animal)
Neither MOTS-c nor AOD-9604 is an approved medicine. All comparisons here are research observations, not usage, dosing or efficacy recommendations.

What the research shows

MOTS-c

EVIDENCE SUMMARY
STRONG
AMPK activation & insulin sensitivity — Consistent animal data. Improved insulin sensitivity and glucose metabolism in rodent models including type 2 diabetes models.
MODERATE
Age-related decline (human correlation) — Human studies show declining serum MOTS-C with age, correlation with metabolic health markers. Not causal.
LIMITED
Exercise mimetic effects — Animal data suggesting MOTS-C mimics some beneficial effects of exercise training. Human trial data pending.

AOD-9604

EVIDENCE SUMMARY
MODERATE
Lipolysis (animal) — Animal studies show stimulation of fat breakdown and inhibition of fat accumulation without HGH-like growth effects.
LIMITED
Human weight loss — Human obesity trials by the original developer did not show statistically significant weight loss vs placebo at tested doses.
LIMITED
Cartilage / joint repair — Some preliminary interest in osteoarthritis research.

Compare prices across EU suppliers

Compare MOTS-c across EU suppliers

19 EU vendors · COA · from €29.95

View prices →

Compare AOD-9604 across EU suppliers

12 EU vendors · COA · from €21.37

View prices →

Frequently asked questions

Is MOTS-c or AOD-9604 better?

Neither is an approved medicine, and “better” depends on the research target. MOTS-c is most associated with AMPK activation & insulin sensitivity, while AOD-9604 is studied for Lipolysis (animal). Compare the evidence tiers and COA-verified EU pricing above rather than assuming one is superior. This is not a usage recommendation.

Why compare MOTS-c and AOD-9604?

Both are studied within Anti-Aging & Longevity research through different mechanisms, so researchers often weigh them against each other. This page sets their evidence, molecular profile, EU legal status and supplier pricing side by side.

Which is cheaper in the EU, MOTS-c or AOD-9604?

Prices vary by supplier, vial size and COA status. MOTS-c is listed from €29.95 across 19 COA-verified EU vendors; AOD-9604 from €21.37 across 12. Open the price pages above to compare current listings — nobody pays us for placement.

Read the full guides

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