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Home / Encyclopedia / Muscle, IGF & Body Composition / Melanotan-1 vs Melanotan-2
⚖️ Muscle, IGF & Body Composition

Melanotan-1 vs Melanotan-2

How do Melanotan-1 and Melanotan-2 compare for Muscle, IGF & Body Composition research? Side-by-side evidence, molecular profile, EU legal status and COA-verified supplier prices — never dosing advice.

At a glance

Melanotan-1

💪 Muscle, IGF & Body Composition
EVIDENCE BASE
SEQUENCE
13 amino acids (α-MSH analogue)
MW
1646.9 g/mol
CAS
75921-69-6
EU STATUS
EMA-approved (Scenesse) · Research grade also available
WADA
Not listed
MIN PURITY
≥98% HPLC
Molecular weight
1646.9 g/mol
CAS number
75921-69-6
PRICE FROM
€39.99 · 1 EU vendors
View prices →

Melanotan-2

💪 Muscle, IGF & Body Composition
EVIDENCE BASE
CLASS
Melanocortin agonist
MW
1024.2 g/mol
CAS
121062-08-6
EU STATUS
Varies by country
UK STATUS
Prescription only
WADA
Prohibited S0
Molecular weight
1024.2 g/mol
CAS number
121062-08-6
Route
Subcutaneous
Half-life (t½)
≈30–60 min
PRICE FROM
€29.9 · 9 EU vendors
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Which fits which research target?

Both Melanotan-1 and Melanotan-2 sit within Muscle, IGF & Body Composition research but are studied for different primary signals. Neither is an approved medicine — compare the evidence, not marketing claims.

PRIMARY RESEARCH SIGNAL
Melanotan-1
Melanogenesis & photoprotection
Melanotan-2
Melanogenesis & tanning
Neither Melanotan-1 nor Melanotan-2 is an approved medicine. All comparisons here are research observations, not usage, dosing or efficacy recommendations.

What the research shows

Melanotan-1

EVIDENCE SUMMARY
STRONG
Melanogenesis & photoprotection — MC1R agonist with robust, dose-dependent skin pigmentation; the basis of the approved analogue afamelanotide.
MODERATE
UV-independent tanning — Stimulates melanin synthesis with reduced UV exposure in human studies.

Melanotan-2

EVIDENCE SUMMARY
STRONG
Melanogenesis & tanning — Potent MC1R agonist producing skin darkening at low cumulative doses in human studies.
MODERATE
Sexual function — MC4R activation with erectogenic effects — the pathway from which bremelanotide (PT-141) was developed.
LIMITED
Appetite & metabolic — Melanocortin-mediated appetite suppression observed; early-stage.

Compare prices across EU suppliers

Compare Melanotan-1 across EU suppliers

1 EU vendors · COA · from €39.99

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Compare Melanotan-2 across EU suppliers

9 EU vendors · COA · from €29.9

View prices →

Frequently asked questions

Is Melanotan-1 or Melanotan-2 better?

Neither is an approved medicine, and “better” depends on the research target. Melanotan-1 is most associated with Melanogenesis & photoprotection, while Melanotan-2 is studied for Melanogenesis & tanning. Compare the evidence tiers and COA-verified EU pricing above rather than assuming one is superior. This is not a usage recommendation.

Why compare Melanotan-1 and Melanotan-2?

Both are studied within Muscle, IGF & Body Composition research through different mechanisms, so researchers often weigh them against each other. This page sets their evidence, molecular profile, EU legal status and supplier pricing side by side.

Which is cheaper in the EU, Melanotan-1 or Melanotan-2?

Prices vary by supplier, vial size and COA status. Melanotan-1 is listed from €39.99 across 1 COA-verified EU vendors; Melanotan-2 from €29.9 across 9. Open the price pages above to compare current listings — nobody pays us for placement.

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