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Home / Encyclopedia / Growth Hormone Axis / Ipamorelin vs Sermorelin
⚖️ Growth Hormone Axis

Ipamorelin vs Sermorelin

How do Ipamorelin and Sermorelin compare for Growth Hormone Axis research? Side-by-side evidence, molecular profile, EU legal status and COA-verified supplier prices — never dosing advice.

At a glance

Ipamorelin

⚡ Growth Hormone Axis
EVIDENCE BASEStrong
CLASS
GHRP (pentapeptide)
MW
711.9 g/mol
CAS
170851-70-4
EU STATUS
Research only
WADA
Prohibited S2
MIN PURITY
≥98% HPLC
Molecular weight
711.9 g/mol
CAS number
170851-70-4
Route
Subcutaneous
Half-life (t½)
≈2 h
PRICE FROM
€23.89 · 16 EU vendors
View prices →

Sermorelin

⚡ Growth Hormone Axis
EVIDENCE BASEStrong
CLASS
GHRH(1-29)
MW
3358 g/mol
CAS
86168-78-7
EU STATUS
Research only
WADA
Prohibited S2
MIN PURITY
≥98% HPLC
Molecular weight
3358 g/mol
CAS number
86168-78-7
Route
Subcutaneous
Half-life (t½)
≈11–12 min
PRICE FROM
€31.45 · 6 EU vendors
View prices →

Which fits which research target?

Both Ipamorelin and Sermorelin sit within Growth Hormone Axis research but are studied for different primary signals. Neither is an approved medicine — compare the evidence, not marketing claims.

PRIMARY RESEARCH SIGNAL
Ipamorelin
GH pulse stimulation
Sermorelin
GH/IGF-1 elevation
Neither Ipamorelin nor Sermorelin is an approved medicine. All comparisons here are research observations, not usage, dosing or efficacy recommendations.

What the research shows

Ipamorelin

EVIDENCE SUMMARY
STRONG
GH pulse stimulation — Robust animal and human data showing selective GH release. No significant effect on cortisol or prolactin unlike other GHRPs.
MODERATE
Bone density (rodents) — Published animal studies show improvements in bone density. Human data limited.
LIMITED
Body composition, recovery — Often combined with GHRH analogues in research. Standalone human data on body composition is limited.

Sermorelin

EVIDENCE SUMMARY
STRONG
GH/IGF-1 elevation — Well-established stimulation of pituitary GH release and downstream IGF-1. Historically used as a diagnostic agent for GH deficiency.
MODERATE
Body composition (with stacking) — Often combined with a GHRP like Ipamorelin. Some data on improved body composition and sleep quality.
LIMITED
Anti-aging claims — Short half-life limits sustained effect. Longevity claims are largely extrapolated from GH/IGF-1 elevation.

Compare prices across EU suppliers

Compare Ipamorelin across EU suppliers

16 EU vendors · COA · from €23.89

View prices →

Compare Sermorelin across EU suppliers

6 EU vendors · COA · from €31.45

View prices →

Frequently asked questions

Is Ipamorelin or Sermorelin better?

Neither is an approved medicine, and “better” depends on the research target. Ipamorelin is most associated with GH pulse stimulation, while Sermorelin is studied for GH/IGF-1 elevation. Compare the evidence tiers and COA-verified EU pricing above rather than assuming one is superior. This is not a usage recommendation.

Why compare Ipamorelin and Sermorelin?

Both are studied within Growth Hormone Axis research through different mechanisms, so researchers often weigh them against each other. This page sets their evidence, molecular profile, EU legal status and supplier pricing side by side.

Which is cheaper in the EU, Ipamorelin or Sermorelin?

Prices vary by supplier, vial size and COA status. Ipamorelin is listed from €23.89 across 16 COA-verified EU vendors; Sermorelin from €31.45 across 6. Open the price pages above to compare current listings — nobody pays us for placement.

Read the full guides

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