Respiratory & Pulmonary.
Lung-targeted peptides in clinical and preclinical development for fibrosis, emphysema, inflammation and mucus regulation.
LTI-03
LTI-03 is Rein Therapeutics' inhaled, first-in-class peptide derived from Caveolin-1, in a global Phase 2 trial for idiopathic pulmonary fibrosis.
PR1P
PR1P is a 12-amino-acid, VEGF-stabilising research peptide studied preclinically for emphysema and acute lung injury.
C6 Peptide
The C6 peptide blocks Hv1 proton channels in neutrophils, studied preclinically to suppress the lung inflammation seen in ARDS.
SP9
SP9 (PEN-SP9) is a Stanford-developed stapled peptide that blocks rapid mucin secretion, studied for asthma, COPD and cystic fibrosis.